Posts Tagged ‘breast cancer threat’

Age and Physical Threat Aspects in Breast Cancer

星期六, 04月 21st, 2012

Age is most likely essentially the most very important overall element related with breast cancer risk. This cancer danger increases
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within the older post-menopausal population. For this cause, all cancer screening suggestions are based primarily on age. Obesity, even so, may well be the single most preventable danger aspect associated with this disease. With the dramatic improve in obesity inside the U.S., this may be the quantity 1 reason for a persistently high incidence in breast cancer. Other physical aspects also play some roles in this cancer threat. These involve height Age and Physical Danger Variables in Breast Cancer , body shape, breast size, and mammographic density
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. These physical aspects are summarized beneath.

Body Weight: A woman’s body weight does impact her risk of breast cancer however the impact is distinct for premenopausal and postmenopausal malignancies. Most research have identified that heavier girls (weighing more than 175 pounds) have a lower threat of this cancer just before menopause and higher risk of this cancer immediately after menopause, in comparison to thinner women (weighing much less than 130 pounds). Considering that 80% of breast cancers occur just after menopause, the negative effects of obesity far outweigh the advantageous effects. The results are the identical regardless of whether body weight is examined directly or if body mass index is utilized to adjust for the effects of height on body weight.

Body Shape: A number of human scientific studies have found that females who carry a lot more of their body fat on their stomach (apple shaped) have greater rates of postmenopausal breast cancer in comparison to women with even more of their body fat around their hips (pear shaped) Age and Physical Risk Components in Breast Cancer . This appears to become correct no matter women’s body weight. The relationship from the location of fat on the body and premenopausal cancer threat has not been clearly determined

Height : A woman’s height has been related with breast cancer risk in a lot of research. Taller females (5′ 9″ or taller) have a smaller improve in threat of both premenopausal and postmenopausal cancer in comparison with shorter females (5′ 3″ or shorter)
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. A person’s height is determined by the interaction of genetics and nutrition. How height might affect this cancer danger is unclear.

Breast Size: There is certainly a popular belief that smaller breasts are at lower danger of breast cancer Age and Physical Risk Factors in Breast Cancer . This theory has been put to use to clarify why ladies with breast implants have a smaller risk of this cancer. Having said that, most research have found no association among breast size and tumor risk. One particular study, however, did acquire an increase inside the threat of malignancy among lean girls with larger breasts. In this study, more than four,000 girls were grouped according to their bra size prior to childbirth
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. Women who had been lean (chest size less than 34 inches) and had bigger breasts (size B, C or bigger cups) were at higher risk of post menopausal breast cancer relative to women of the same chest size with an A or smaller cup size. Females with other chest sizes had no association among breast cup size and cancer threat. Extra scientific studies are necessary to confirm these results.

Mammographic density: Various epidemiological scientific studies have shown that breast density as measured on mammograms is usually a considerable threat factor for breast cancer. The danger of cancer connected with the highest category of density has been estimated to be much greater than in the lowest density category. Mammographic density appears to become predictive for creating invasive cancer immediately after DCIS (ductal carcinoma in situ). Increasing density is connected with growing breast cancer danger in both premenopausal
and postmenopausal females
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, using the impact persisting for ten years just after mammography. Mammographic density has also been shown to be a threat factor for this cancer in women with a family members history
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from the disease. Mammographic density is in all probability critical even in patients who’re BRCA gene positive. The reality is, mammographic density may perhaps essentially have a substantial heritable component.=

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